Research & Development

The experience and competency is used from all spheres, that differentiate from other service research & diagnostic centre. THCC supports undergraduate, postgraduate and research students with their academic research projects as per their needs and is also actively involved in conducting conferences, workshops and training in its focus areas.

Current research areas

  • Method Development for Antimicrobial and Preservative Efficacy Testing
  • Quantitative Microbial Risk Analysis(QMRA) for infectious disease
  • Developing Competence in Proficiency Testing for Microbiological Tests for multidrug resistance microbes


  • Serotyping and antibiotic susceptibility patterns of Vibrio and Shigella isolates from diarrheal patients visiting a Tropical and infectious Diseases Hospital in Central Nepal.
  • Comparison of Nasal colonization of Methicillin- Resistant Staphylococcus aureus in HIV- infected and NON- HIV Patients Attending the National Public Health laboratory of Central Nepal
Completed Research Project

Mr Hari Paudel
Research project
  • Antibiotics resistance profile of Pseudomonas aeruginosa isolated from soil sample of mountain ranges.
  • Hospital acquired infection associated with Extended spectrum Beta-lactamase(ESBL) producing Staphylococcus aureus.
  • Isolation and Screening of Vancomycin-resistant Enterococci (VRE) from stool sample
  • Performing quantitative risk analysis for microbes from water samples
Focus Area
  • Nosocomial infection and their association with Beta lactamase enzyme
  • Risk analysis for microbes from environment samples such as soil, water.
  • Isolation and Screening of community acquired infection
  • Designing research project, Data analysis & preparation of Lab reports

Mr Saroj Dhakal
Research project
  • Elisa For IgM-class antibody to Hepatists D virus, with epitope expressed in Campylobacter jejuni
Focus Area
  • Biochemical analysis of body fluids
  • Therapeutic drug monitoring, making observation & measurement
  • ELISA , Electrophoresis method for identification of antibodies using fluorescent molecule

Mr Jeevan Ter
Research project
  • Extended spectrum Beta-lactamase (ESBL) production by bacterial pathogens associated with Bacteraemia in Chronic Kidney disease(CKD) patient visiting tertiary Care Hospital
  • Comparing Colonisation of Extended Spectrum Beta- Lactamase producing Escherichia Coli in immunosuppressed and non-immunosuppressed patients.
  • Isolation and characterisation of bacteria, fungi and yeast from environment samples making measurement and observation with specific culture media used.
  • Characteristics and growth of microbes associated with Urinary tract infection testing their multidrug resistance pattern (MDR).
  • Prevalence of Vibrio cholerae and Shigella spp. in HIV- sero positive patients.
Focus Area
  • Designing Research Project, Data Analysis & supervising postgraduate research student
  • Conducting experiments for development of antimicrobial testing method
  • Studying growth, culture, virulence & characteristic of microorganism such as bacteria, fungi & yeast
  • Examining microorganism, understanding their biochemical enzymes for therapeutic purpose & presenting finding in several symposia

Mr Suman Adhikari
Research project
  • Characterization and activity of antimicrobial polypeptide of Bacillus spp from soil of terai region of Nepal
  • Antibiotic susceptibility patterns of Salmonella and Shigella isolates from patients suffering from septicemia visiting a Tropical Hospital
Focus Area
  • Antibiotic resistant infections
  • drug development with new antimicrobial agents
  • Emerging diseases their pathogenesis
  • Data analysis, designing project

Mr Binod Rayamajhee
Research project
  • Developing molecular proficiency testing for microbiological tests for multi drug and tropical disease
  • Serotyping and antibiotic susceptibility patterns of Vibrio and Shigella isolates from diarrheal patients visiting a tropical and infectious diseases hospital in Central Nepal
  • Comparison of Nasal colonization of Methicillin-Resistant Staphylococcus aureus in HIV-infected and NON-HIV patients Attending the National Public Health laboratory of Central Nepal
Focus Area
  • clinical application of molecular diagnosis
  • infectious and tropical diseases
  • multi drug resistance infection
  • Designing project, data analysis
  • Antimicrobial testing method

Mr Sandeep Thapa
Research project
  • Isolation and Screening of Methicillin resistance Staphylococcus aureus from wound sample associated with resistant geneproficiency testing for microbiological tests for multi drug and tropical disease
Focus Area
  • Analysis and characterization of outbreak strain
  • molecular analysis of drug resistant gene
  • Staining techniques
  • data analysis